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Bakay
Movement Disorder Surgery

Table of Contents


1. History of Surgery for Movement Disprders
Pre-stereotactic Surgery
Early stereotactic Surgery
Post L-dopa era
Resurgence of stereotactic surgery and future directions

2. Rationale for Surgery
Anatomy of the thalamus and basal ganglion
Electrophysiology of the thalamus and basal ganglion
Pathophysiological changes
Lesion vs. DBS

3. Setting up Practice
Capital Expenses
Building a Program
Generating Referrals
Billing and Coding

4. Patient Selection
Signs and Symptoms
L-dopa response
Neuroimaging
Neuropsychological Testing
CAPIT and other special testes

5. Preparation for Surgery
Selection of a Stereotactic Frame
Applying the Frame
CT/'MR Imaging
Selecting Targets
How to iron out distortion problems in the MRI

6. Stereotactic Surgery with Microelectrode Recordings
Microelectrode Recording
Intraoperative Testing
Lesioning
Implantation of the Lead
Securing the Lead
Extraoperative Testing
Implanting the IPG

7. Stereotactic Surgery with Microelectrode Recording
Impedance Testing
Electrophysiologic Testing
Intraoperative Target Adjustments
Advantages and Disadvantages

8. Programming the IPG
BDS Mechanism of Action
Interrogating the IPG
Initial Settings
Adjustments
Trouble shooting

9. Avoiding Complications and Correcting Errors
Controlling Blood Pressure and Hemostasis
Dejection of Wire ractures
Repair of Fractures and Migrations
Battery Changes
Treating Infections
Development of Tolerance

10. Results and Complications
Improvement and Complications with VIM DBS
Improvement and Complications with Gpi DBS
Improvement and Complications with STN DBS

11. Essential Terror
Patient Selection
Electrophysiology
Lesioning vs DBS
Results, recurrences and complications

12. Dystonia
Primary and Secondary
Anesthesia Concerns
Electrophysiology
Special IPG Programming

13. Gamma Knife
Indications and Controversies
Target Selection
Dose and Distribution
Results and Complications

14. Neural Transplantation
Animal Studies
Clinical Studies
Adrenal Medullary
Fetal Mesencephalic
Alternative Tissues
Stem Cells

15. Gene Therapies
Vectors
Replacement Strategies
Repair Strategies
Preventive Strategies

 
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