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Antunovic
Magnetic Resonance in the Diagnosis of CNS Disorders

Table of Contents


A. MAGNETIC RESONANCE IN THE DIAGNOSIS OF THE BRAIN
AND CRANIO-CERVICAL JUNCTION PATHOLOGY
Gradimir Dragutinovic, Vaso Antunovic

GENERAL PRINCIPLES
1. Introduction
2. History
3. Operating principles of the Magnetic Resonance
4. Magnetic Resonance imaging of the normal anatomy structures
5. Artifacts
6. Technique of the MR examination
7. Selection of sequences for the MR examination
8. Paramagnetic contrast in the magnetic resonance imaging

I.MALFORMATIONS 25
Vaso Antunovic, Gradimir Dragutinovic, Zvonimir Levic
1. Midline closure defects (neural tube defects, dysraphic disorders)
a) Encephalocele, meningocele, meningoencephalocele
b) Cerebellar agenesis and hypoplasia
c) Dandy-Walker Syndrome
d) Retrocerebellar Arachnoidal Pouch (Blakes cyst)
e) Arnold-Chiari Malformation
2. Malformation of the commisures and midline structures
a) Corpus callosum agenesis
b) Cavum septi pellucidi, cavum verge and cavum veli interpositi
3. Anomalies of the cell migration
4. Destructive lesions
a) Porencephaly
5. Neuroectodermal dysplasia; phakomatosis
a) Tuberous sclerosis - Morbus Bourneville
b) Neurofibromatosis
6. Miscellaneous abnormalities
a) Hydrocephalus
b) Arachnoidal cyst
c) Basilar invagination

II. CEREBROVASCULAR DISEASES OF THE BRAIN
Gradimir Dragutinovic, Zvonimir Levic, Ivan Piscevic
1. Arterial blood flow disorders
2. Venous blood flow disorders
3. Hemorrhage
4. Vascular malformations
a) A-V malformation (angioma)
b) Aneurysms
c) Varices of the Galens vein
d) Venous angioma
e) Capillary telangiectasia
f) Cavernoma
5. Miscellaneous

III. TRAUMA
Miroslav Samardzic, Gradimir Dragutinovic, Vaso Antunovic
1. Brain contusion
2. Brain trauma caused by drowning (Submersio)

IV. INTRACRANIAL INFECTION
Branislav Nestorovic, Gradimir Dragutinovic, Lukas Rasulic
1. Bacterial infections
a) Abscessus cerebri
b) Epidural and subdural empyema
c) Meningovascular Neurosyphilis
d) Borreliosis
2. Parasytoses
a) Cysticercosis
b) Echinococcosis
c) Trichinosis
3. Neuro AIDS
4. Sarcoidosis

V. DEGENERATIVE DISEASES OF THE BRAIN
Zvonimir Levic , Gradimir Dragutinovic
1. Primary neuronal disease (gray matter)
a) Congenital diseases

b) Acquired neuronal diseases (gray matter)
b-1 Alzheimer's disease
b-2 Picks disease
b-3 Creutzfeldt-Jacobs disease
2. Primary diseases of the basal ganglia and brainstem
a) Congenital diseases
a-6 Olivo-ponto-cerebellar degeneration
b) Acquired and unexplained causes
b-1 Central pontine myelinosis
3. Primary involvement with no sites of predilection
a) Congenital diseases
b) Acquired and unexplained causes
b-1 Systemic lupus erythematodes
4. Myelin diseases (white matter)
a) Congenital white matter diseases
a- 1, 2, 3 Leukodistrophies
b) Acquired and unknow causes
b-1 Sclerosis Multiple
b-3 Hypertensive cerebrovascular disease (Binswangers disease and Multiinfarction dementia)
b-5 Postinfective encephalomyelitis
b-6 Postirradiation sequels
b-7 Necrotizing encephalopathies
VI. BRAIN TUMORS
Miodrag Rakic, Vaso Antunovic, Ljiljana Djordjic, Gradimir Dragutinovic
Craniocervical and cervicocranial tumors
1. Tumors of neuroepithelial origin
a) Astrocytic tumors
a-1 Astrocytoma
a-2 Glioma of the optic nerve and glioma of the optic chiasm
b) Oligodendroglial tumors
b-1 Oligodendroglioma
c) Poorly differentiated and embryonic tumors
c-1 Glioblastoma
c-2 PNET - Medulloblastoma
d) Ependymal tumors
d-1 Ependymoma
e) Chorioid plexus tumors
e-1 Chorioid plexus papilloma
f) Pineal cell tumor
f-1 Pinealoma
f-2 Other tumors of the pineal region
Neuronal tumors
2. Tumors of nerve sheath origin
Neurinoma
3. Meningeal tumors
a) Meningioma
a-1 Meningioma
a-2 Atypical meningioma
a-3 Malignant meningioma
4. Tumors of vascular origin
a) Hemangioblastoma
b) Hemangiopericytoma
5. Germinal cell tumors
a) Germinoma
b) Teratoma
6. Malformation and miscellaneous tumors
a) Craniopharyngioma
b) Colloidal cyst
c) Lipoma
d) Dermoid, epidermoid and neuroenteric cysts
d-1 Dermoid cyst
d-2 Epidermoids
d-3 Neuroenteric cysts
7. Primary malignant lymphoma
8. Metastases

VII. TUMORS OF THE POSTERIOR CRANIAL FOSSA
Vaso Antunovic, Gradimir Dragutinovic, Miodrag Rakic
1. Intraaxial posterior fossa tumors
a) Medulloblastoma
b) Ependymoma
c) Papilloma of the chorioid plexus
2. Extraaxial posterior fossa tumors
a) Neurinoma of the acoustic nerve
b) Neurofibroma
c) Meningioma
d) Epidermoid
e) Chordoma
f) Glomus jugulare tumor
3. Tumors of the cerebellar hemispheres
a) Astrocytoma
b) Hemangioblastoma
c) Cavernoma
d) Angioma
e) Metastases
4. Primary tumors of the brainstem

VIII. TUMORS OF THE CRANIOCERVICAL JUNCTION
Gradimir Dragutinovic, Miodrag Rakic, Ljiljana Djordjic
a) Neurinoma
b) Meningioma mixtus
c) Meningioma
d) A-V malformation
e) Ependymoma

IX. EXTRACRANIAL TUMORS WITH INTRACRANIAL PROPAGATION
Vaso Antunovic, Gradimir Dragutinovic, Ivan Piscevic
a) Chordoma
b) Nasopharyngeal adenocarcinoma
c) Squamous cell carcinoma of nasopharynx
d) Squamous cell carcinoma of maxilla and zygomatic bone
e) Benign tumor of the pterygoid fossa
f) Optic nerve glioma

X. TUMORS OF THE HYPOPHYSIS
Gradimir Dragutinovic, Vaso Antunovic, Miroslav Samardzic
a) HGH-Producing Adenomas
b) Prolactinomas
c) ACTH-Producing adenomas
d) TSH-Producing adenomas
e) FSH and LH-Producing adenomas
f) Hormonally inactive adenomas
g) Pathologic lesions of the hypophyseal stalk
h) Empty Sella Syndrome
i) MR controls

XI. TEMPORAL LOBE EPILEPSY
Zvonimir Levi´c, Gradimir Dragutinovi´c, Lukas Rasuli´c
a) Arachnoidal cyst
b) Spontaneous intracerebral hemorrhage
c) Aneurysm of the internal carotid artery
d) Cavernoma
e) Trauma
f) Tumor
g) Postoperative defect

XII. MR ANGIOGRAPHY OF THE ENDOCRANIUM AND NECK
Gradimir Dragutinovic, Vaso Antunovic, Miodrag Rakic

XIII. MR CONTROLS FOLLOWING THERAPY
Gradimir Dragutinovic, Ljiljana Djordjic, Lukas Rasulic

XIV. MR IN CHILDREN
Gradimir Dragutinovic, Zvonimir Levic, Vaso Antunovic
a) Retrocerebellar arachnoidal pouch
b) Arachnoidal Cyst
c) Cryptic AVM
d) Borreliosis
e) Leukodystrophy
f) Meningiomas
g) Pilocytic Astrocytomas
h) Craniopharyngiomas
i) Astrocytoma of the cervical cord

B) MAGNETIC RESONANCE IN THE DIAGNOSIS OF THE PATHOLOGY
OF THE SOFT TISSUES INSIDE SPINAL CANAL
Gradimir Dragutinovic, Vaso Antunovic, Zvonimir Levic

GENERAL PRINCIPLES
1. Introduction
2. Neuroradiologic examination of the spine
3. Magnetic Resonance of normal anatomy structures
4. Artifacts
5. Technique of MR examination
6. Choice of sequences for MR imaging
7. Paramagnetic contrast in the MR imaging of the spine

I. MALFORMATIONS
Ljiljana Djordjic, Gradimir Dragutinovic, Lukas Rasulic
A) Midline closure defects of the spine (I) and of the spinal cord (II)
B) Neuroectodermal dysplasias

II. VASCULAR DISEASES OF MEDULLA SPINALIS
Zvonimir Levic, Gradimir Dragutinovic, Vaso Antunovic
a) Infarction of the medulla spinalis
b) Hemorrhage
c) A-V malformations
Cavernous angioma

III. SPINAL TRAUMA
Lukas Rasulic, Gradimir Dragutinovic, Miroslav Samardzic

IV. INFLAMMATORY DISEASES
Gradimir Dragutinovic, Zvonimir Levic, Vaso Antunovic
a) Myelitis
b) Parasitoses

V. DEMYELINATION DISEASES
Zvonimir Levic, Gradimir Dragutinovic
a) Sclerosis multiplex
b) Myelopathy and myelomalacia

VI. TUMORS
Vaso Antunovic, Gradimir Dragutinovic, Miodrag Rakic
a) Intramedullar tumors
b) Intradural extramedullar tumors
c) Extradural tumors
d) Primary vertebral tumors
e) Secondary spinal tumors

VII. DEGENERATIVE DISEASES OF THE SPINE
Miroslav Samardzic, Lukas Rasulic, Gradimir Dragutinovic
Disk herniation
a) Introduction
a-1 Cervical disk herniation
a-2 Thoracic disk herniation
a-3 L-S discus herniae
b) Neuroradiological examination
c) Magnetic resonance imaging
c-1 General remarks
c-2 Examination technique and sequences
c-3 MR of normal anatomy structures
c-4 MRI of disk herniation
c-5 MRI controls

VIII. MR ANGIOGRAPHY OF THE SPINE
Gradimir Dragutinovic, Vaso Antunovic, Miodrag Rakic

IX. POSTOPERATIVE CHANGES AND CONTROLS

 
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