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Stuttgart –With the release of Science of Synthesis (SOS) 4.2, Thieme Chemistry once again updates and expands its unique full-text resource for methods and experimental procedures in synthetic organic chemistry. Available as of November 2015, Science of Synthesis 4.2 will include the latest Knowledge Updates and additions from the Reference Library – a total of approximately 2,400 printed pages of new content.

The latest release of Science of Synthesis will see the addition of SOS Knowledge Updates comprising approximately 500 printed pages. It includes a new chapter on the synthesis and application of N-heterocyclic carbene borane complexes, a novel type of compound that has attracted great interest in recent years. A completely revised chapter on benzo[b]furans incorporates traditional as well as new methods for synthesizing this important class of compounds. The updating process is guided by strict criteria to ensure that only the best and most reliable synthetic methods are included in SOS. New content will continually be added to the digital version, which prevails as the most up-to-date evaluated digital reference work available, reflecting the latest developments in synthetic methodology.

The Science of Synthesis Reference Library has also been expanded to include three new volumes comprising a total of 1,960 printed pages. Biocatalysis in Organic Synthesis Volumes 1 through 3, edited by K. Faber, W.-D. Fessner and N. Turner, with contributions by 121 expert authors, presents a broad overview on the state of the art in enzymatic methods for asymmetric synthesis. As new biocatalyst platforms move from academic laboratories into practical application, new biocatalysts will become more widely available, offering alternatives to expensive or toxic chemical reagents. Addressing academics and industrial researchers alike, Biocatalysis in Organic Synthesis offers critical expert reviews of organic transformations, including experimental procedures.

To allow users to efficiently mine this wealth of content, Thieme has implemented a DOI operator making the search for Digital Object Identifiers possible. Additionally, improvements to wildcard searching have been made enabling this text-search feature to provide even more accurate and relevant results.

To get access to Science of Synthesis 4.2 or a free trial please visit:
For more information about Science of Synthesis please visit the Website at


About Thieme
Thieme Publishing Group is a medical and scientific publishing house employing more than 900 staff and maintaining offices in seven cities, including New York, Delhi, Rio and Stuttgart, Germany. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing. Thieme publishes 150 peer-reviewed journals and more than 450 new books annually. The company has a rapidly growing array of web-based products in medicine and science. State-of-the-art online products include eNeurosurgery, Medlantis, Thieme E-Journals, Thieme Electronic Book Library, the medical student website and Thieme Teaching Assistant, an innovative web-based platform for faculty. For more information about Thieme, please visit

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